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NewEast Biosciences are specialized in generating protein configuration-specific monoclonal antibodies that recognize active (GTP-bound) G proteins (including Ras-superfamily small GTPases and heterotrimeric G proteins). These unique antibodies do not recognize the inactive (GDP-bound) G proteins. These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections. Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies. |
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| RhoA, Rac1, Gαo, Gαs, Gαz, Gαi, Gα13, Cdc42, Rab5, Ran, RheB, B-Raf (V600E), Ras(G12D), Ras(G13D), TP53(R282W), EGFR(G863D), EGFR(L861Q), cAMP, cGMP, Apo A1 EIA Kit |
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NewEast Biosciences |
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Contact us |
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United States |
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